Are neuropsychiatric symptoms in dementia linked to CSF biomarkers of synaptic and axonal degeneration?

Are neuropsychiatric symptoms in dementia linked to CSF biomarkers of synaptic and axonal degeneration?

Abstract Background The underlying disease mechanism of neuropsychiatric symptoms (NPS) in dementia remains unclear. Cerebrospinal fluid (CSF) biomarkers for synaptic and axonal degeneration may provide novel neuropathological information for their occurrence. The aim was to investigate the relation...

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Bibliographic Details
Main Authors: Victor Bloniecki, Henrik Zetterberg, Dag Aarsland, Patrizia Vannini, Hlin Kvartsberg, Bengt Winblad, Kaj Blennow, Yvonne Freund-Levi
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Alzheimer’s Research & Therapy
Subjects:
NPS
CSF biomarkers
Synaptic and axonal dysfunction
Neurogranin
GAP-43
Neurofilament
Online Access:http://link.springer.com/article/10.1186/s13195-020-00718-y

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http://link.springer.com/article/10.1186/s13195-020-00718-y

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