Niosomal formulation of amphotericin B alone and in combination with glucantime: In vitro and in vivo leishmanicidal effects

Niosomal formulation of amphotericin B alone and in combination with glucantime: In vitro and in vivo leishmanicidal effects

This study aimed to evaluate the efficacy of glucantime and amphotericin B (AmB) encapsulated in niosome against cutaneous leishmaniasis (CL) using in vitro and in vivo models. The niosomal formulations of the drugs alone and in combination were prepared and characterized. Subsequent to the examinat...

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Bibliographic Details
Main Authors: Mahshid Mostafavi, Iraj Sharifi, Saeedeh Farajzadeh, Payam Khazaeli, Hamid Sharifi, Elnaz Pourseyedi, Sina Kakooei, Mehdi Bamorovat, Alireza Keyhani, Maryam Hakimi Parizi, Ahmad Khosravi, Ali Khamesipour
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Cutaneous leishmaniasis
Niosome
Amphotericin B
Glucantime
In vivo
In vitro
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219313939

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http://www.sciencedirect.com/science/article/pii/S0753332219313939

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