A protocol for representative sampling of solid tumors to improve the accuracy of sequencing results

A protocol for representative sampling of solid tumors to improve the accuracy of sequencing results

Summary: Owing to spatial segregation of tumor subclones, solid tumor sampling using formalin-fixed, paraffin-embedded blocks is often inadequate to represent the genomic heterogeneity of solid tumors. We present an approach, representative sampling, to dissect and homogenize leftover residual surgi...

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Bibliographic Details
Main Authors: Lisa L. Gallegos, Ashley Gilchrist, Lavinia Spain, Stacey Stanislaw, Samantha M. Hill, Vanessa Primus, Carol Jones, Somya Agrawal, Zayd Tippu, Aoune Barhoumi, Glenn Noel-Storr, Nelson R. Alexander, Samra Turajlic
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:STAR Protocols
Subjects:
Cancer
Clinical Protocol
Flow Cytometry/Mass Cytometry
Genomics
Sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721003312

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http://www.sciencedirect.com/science/article/pii/S2666166721003312

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