Knockdown of Laminin gamma-3 (Lamc3) impairs motoneuron guidance in the zebrafish embryo [version 1; referees: 2 approved, 2 approved with reservations]
Background: Previous work in the zebrafish embryo has shown that laminin γ-3 (lamc3) is enriched in endothelial cells marked by expression of fli1a, but the role of Lamc3 has been unknown. Methods: We use antisense morpholino oligonucleotides, and CRISPR/Cas9 mutagenesis of F0 embryos, to create zeb...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wellcome
2017-11-01
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| Series: | Wellcome Open Research |
| Subjects: | |
| Online Access: | https://wellcomeopenresearch.org/articles/2-111/v1 |