Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase.

The complement cascade is crucial for clearance and control of invading pathogens, and as such is a key target for pathogen mediated host modulation. C3 is the central molecule of the complement cascade, and plays a vital role in opsonization of bacteria and recruitment of neutrophils to the site of...

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Bibliographic Details
Main Authors: Nicola N Lynskey, Mark Reglinski, Damien Calay, Matthew K Siggins, Justin C Mason, Marina Botto, Shiranee Sriskandan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5555575?pdf=render