Microfluidic Tumor-on-a-Chip Model to Study Tumor Metabolic Vulnerability

Tumor-specific metabolic adaptations offer an interesting therapeutic opportunity to selectively destroy cancer cells. However, solid tumors also present gradients of nutrients and waste products across the tumor mass, forcing tumor cells to adapt their metabolism depending on nutrient availability...

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Bibliographic Details
Main Authors: Jose M Ayuso, Shujah Rehman, Mehtab Farooqui, María Virumbrales-Muñoz, Vijayasaradhi Setaluri, Melissa C Skala, David J Beebe
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/23/9075