Insertion Defects of Mitochondrially Encoded Proteins Burden the Mitochondrial Quality Control System

The mitochondrial proteome contains proteins from two different genetic systems. Proteins are either synthesized in the cytosol and imported into the different compartments of the organelle or directly produced in the mitochondrial matrix. To ensure proteostasis, proteins are monitored by the mitoch...

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Bibliographic Details
Main Authors: Braulio Vargas Möller-Hergt, Andreas Carlström, Tamara Suhm, Martin Ott
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/7/10/172