DDS promotes longevity through a microbiome-mediated starvation signal

DDS promotes longevity through a microbiome-mediated starvation signal

The antibiotic diaminodiphenyl sulfone (DDS) is used in combination with other antibiotics as a first line treatment for leprosy. DDS has been previously reported to extend lifespan in Caenorhabditis elegans through inhibition of pyruvate kinase and decreased mitochondrial function. Here we report a...

Full description

Bibliographic Details
Main Authors: Haeri Choi, Sung Chun Cho, Young Wan Ha, Billie Ocampo, Shirley Park, Shiwen Chen, Christopher F. Bennett, Jeehae Han, Ryan Rossner, Jong-Sun Kang, Yun-ll Lee, Sang Chul Park, Matt Kaeberlein
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-01-01
Series:Translational Medicine of Aging
Online Access:http://www.sciencedirect.com/science/article/pii/S2468501119300045

Internet

http://www.sciencedirect.com/science/article/pii/S2468501119300045

Similar Items