DDS promotes longevity through a microbiome-mediated starvation signal
The antibiotic diaminodiphenyl sulfone (DDS) is used in combination with other antibiotics as a first line treatment for leprosy. DDS has been previously reported to extend lifespan in Caenorhabditis elegans through inhibition of pyruvate kinase and decreased mitochondrial function. Here we report a...
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Bibliographic Details
Main Authors: |
Haeri Choi,
Sung Chun Cho,
Young Wan Ha,
Billie Ocampo,
Shirley Park,
Shiwen Chen,
Christopher F. Bennett,
Jeehae Han,
Ryan Rossner,
Jong-Sun Kang,
Yun-ll Lee,
Sang Chul Park,
Matt Kaeberlein |
Format: | Article
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Language: | English |
Published: |
KeAi Communications Co., Ltd.
2019-01-01
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Series: | Translational Medicine of Aging
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2468501119300045
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