The evaluation of the factors that cause aggregation during recombinant expression in <it>E. coli </it>is simplified by the employment of an aggregation-sensitive reporter

<p>Abstract</p> <p>Background</p> <p>The yields of soluble recombinant proteins expressed in bacteria are often low due to the tendency of the heterologous proteins to form aggregates. Therefore, aggregation reporters have been envisaged to simplify the comparison among...

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Bibliographic Details
Main Authors: Martinez Lucia, Schultz Tina, de Marco Ario
Format: Article
Language:English
Published: BMC 2006-09-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/5/1/28