Cimetidine and Clobenpropit Attenuate Inflammation-Associated Colorectal Carcinogenesis in Male ICR Mice

Cimetidine and Clobenpropit Attenuate Inflammation-Associated Colorectal Carcinogenesis in Male ICR Mice

Histamine and histamine receptors (Hrhs) have been identified as critical molecules during inflammation and carcinogenesis. This study was conducted to determine the effects of Hrh1-Hrh3 antagonists on inflammation-associated colorectal carcinogenesis. Male ICR mice were treated with azoxymethane (A...

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Bibliographic Details
Main Authors: Takuji Tanaka, Takahiro Kochi, Yohei Shirakami, Takayuki Mori, Ayumi Kurata, Naoki Watanabe, Hisataka Moriwaki, Masahito Shimizu
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Cancers
Subjects:
histamine receptors
antagonists
chemoprevention
colorectal cancer
azoxymethane
dextran sodium sulfate
inflammatory bowel disease
Online Access:http://www.mdpi.com/2072-6694/8/2/25

Internet

http://www.mdpi.com/2072-6694/8/2/25

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