Enhanced and controlled chromatin extraction from FFPE tissues and the application to ChIP-seq

Enhanced and controlled chromatin extraction from FFPE tissues and the application to ChIP-seq

Abstract Background Epigenetic dysregulation is involved in the etiology and progression of various human diseases. Formalin-fixed paraffin-embedded (FFPE) samples represent the gold standard for archiving pathology samples, and thus FFPE samples are a major resource of samples in clinical research....

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Bibliographic Details
Main Authors: Jian Zhong, Zhenqing Ye, Chad R. Clark, Samuel W. Lenz, Justin H. Nguyen, Huihuang Yan, Keith D. Robertson, Gianrico Farrugia, Zhiguo Zhang, Tamas Ordog, Jeong-Heon Lee
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Genomics
Subjects:
FFPE tissues
Chromatin extraction
ChIP-seq
Online Access:http://link.springer.com/article/10.1186/s12864-019-5639-8

Internet

http://link.springer.com/article/10.1186/s12864-019-5639-8

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