Symmetric exchange of multi-protein building blocks between stationary focal adhesions and the cytosol

How can the integrin adhesome get self-assembled locally, rapidly, and correctly as diverse cell-matrix adhesion sites? Here, we investigate this question by exploring the cytosolic state of integrin-adhesome components and their dynamic exchange between adhesion sites and cytosol. Using fluorescenc...

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Bibliographic Details
Main Authors: Jan-Erik Hoffmann, Yessica Fermin, Ruth LO Stricker, Katja Ickstadt, Eli Zamir
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/02257