Miro, a Rho GTPase genetically interacts with Alzheimer's disease-associated genes (Tau, Aβ42 and Appl) in Drosophila melanogaster

Miro (mitochondrial Rho GTPases), a mitochondrial outer membrane protein, facilitates mitochondrial axonal transport along the microtubules to facilitate neuronal function. It plays an important role in regulating mitochondrial dynamics (fusion and fission) and cellular energy generation. Thus, Miro...

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Bibliographic Details
Main Authors: Komal Panchal, Anand Krishna Tiwari
Format: Article
Language:English
Published: The Company of Biologists 2020-09-01
Series:Biology Open
Subjects:
tau
Online Access:http://bio.biologists.org/content/9/9/bio049569