CYP3A5*3, CYP3A4*1B and MDR1 C3435T Genotype Distributions in Ecuadorians

Polymorphisms in CYP3A genes, such as CYP3A5 and CYP3A4, as well as in the MDR1 gene, which encodes for P-glycoprotein, have been implicated as genetic markers in several disorders. Differences in the frequency distribution of the allelic variants CYP3A5*3, CYP3A4*1B, and MDR1 3435T have been demons...

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Bibliographic Details
Main Authors: Blanca Sinués, Jorge Vicente, Ana Fanlo, Esteban Mayayo-Sinués, Fabricio González-Andrade, Dora Sánchez-Q, Begoña Martínez-Jarreta
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2008/750804