Human NK cell lytic granules and regulation of their exocytosis.

Natural killer (NK) cells form a subset of lymphocytes that play a key role in immuno-surveillance and host defense against cancer and viral infections. They recognize stressed cells through a variety of germline-encoded activating cell surface receptors and utilize their cytotoxic ability to elimin...

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Bibliographic Details
Main Authors: Konrad eKrzewski, John Ernest Coligan
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00335/full