An Efficient Synthesis and Reactions of Novel Indol-ylpyridazinone Derivatives with Expected Biological Activity
Reaction of 4-anthracen-9-yl-4-oxo-but-2-enoic acid (1) with indole gave the corresponding butanoic acid 2. Cyclocondensation of 2 with hydrazine hydrate, phenyl hydrazine, semicarbazide and thiosemicarbazide gave the pyridazinone derivatives 3a-d. Reaction of 3a with POCl3 for 30 min gave the chlor...
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| Format: | Article |
| Language: | English |
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MDPI AG
2007-01-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/12/1/25/ |