Modeling of the HIV-1 Life Cycle in Productively Infected Cells to Predict Novel Therapeutic Targets

Modeling of the HIV-1 Life Cycle in Productively Infected Cells to Predict Novel Therapeutic Targets

There are many studies that model the within-host population dynamics of Human Immunodeficiency Virus Type 1 (HIV-1) infection. However, the within-infected-cell replication of HIV-1 remains to be not comprehensively addressed. There exist rather few quantitative models describing the regulation of...

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Bibliographic Details
Main Authors: Olga Shcherbatova, Dmitry Grebennikov, Igor Sazonov, Andreas Meyerhans, Gennady Bocharov
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pathogens
Subjects:
HIV-1
intracellular replication
mathematical model
sensitivity analysis
antiviral targets
Online Access:https://www.mdpi.com/2076-0817/9/4/255

Internet

https://www.mdpi.com/2076-0817/9/4/255

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