20(S)-Protopanaxadiol Phospholipid Complex: Process Optimization, Characterization, In Vitro Dissolution and Molecular Docking Studies

20(S)-Protopanaxadiol Phospholipid Complex: Process Optimization, Characterization, In Vitro Dissolution and Molecular Docking Studies

20(S)-Protopanaxadiol (PPD), a bioactive compound extracted from ginseng, possesses cardioprotective, neuroprotective, anti-inflammatory, antiestrogenic, anticancer and anxiolytic effects. However, the clinical application of PPD is limited by its weak aqueous solubility. In this study, we optimized...

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Bibliographic Details
Main Authors: Yiqiong Pu, Xitong Zhang, Qi Zhang, Bing Wang, Yuxi Chen, Chuanqi Zang, Yuqin Wang, Tina Ting-Xia Dong, Tong Zhang
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Molecules
Subjects:
20(S)-protopanaxadiol
phospholipid complex
central composite design
DSC
molecular docking
Online Access:http://www.mdpi.com/1420-3049/21/10/1396

Internet

http://www.mdpi.com/1420-3049/21/10/1396

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