Dynamic Evaluation of Notch Signaling-Mediated Angiogenesis in Ischemic Rats Using Magnetic Resonance Imaging

Objective. The Notch signaling pathway is involved in angiogenesis induced by brain ischemia and can be efficiently inhibited by the γ-secretase inhibitor N-[N-(3,5-difluorophenacetyl)-1-alanyl]-S-phenylglycine t-butyl ester (DAPT). The aim of the present study was to noninvasively investigate the e...

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Main Authors: Jia-qi Tian, Jia-jun Zheng, Xiao-zhu Hao, Le-kang Yin, Xiao-xue Zhang, Chan-chan Li, Xiao-yuan Feng, Min Jiang, Hua-ping Sun, Kang Zheng, Yan-mei Yang
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2018/8351053