Transgenic Tmc2 expression preserves inner ear hair cells and vestibular function in mice lacking Tmc1

Transgenic Tmc2 expression preserves inner ear hair cells and vestibular function in mice lacking Tmc1

Abstract Recent work has demonstrated that transmembrane channel-like 1 protein (TMC1) is an essential component of the sensory transduction complex in hair cells of the inner ear. A closely related homolog, TMC2, is expressed transiently in the neonatal mouse cochlea and can enable sensory transduc...

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Bibliographic Details
Main Authors: Yukako Asai, Bifeng Pan, Carl Nist-Lund, Alice Galvin, Andrei N. Lukashkin, Victoria A. Lukashkina, Tianwen Chen, Wu Zhou, Hong Zhu, Ian J. Russell, Jeffrey R. Holt, Gwenaelle S. G. Géléoc
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-28958-x

Internet

https://doi.org/10.1038/s41598-018-28958-x

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