Experimental evidence of obstructive sleep apnea syndrome as a second hit accomplice in nonalcoholic steatohepatitis pathogenesis** Bevans S, Nanayakkara A, Li J, Smith PL, Torbenson MS, Polotsky VY. Chronic intermittent hypoxia causes hepatitis in a mouse model of diet-induced fatty liver. Am J Physiol Gastrointest Liver Physiol. 2007; 293:G871-G877.

Experimental evidence of obstructive sleep apnea syndrome as a second hit accomplice in nonalcoholic steatohepatitis pathogenesis** Bevans S, Nanayakkara A, Li J, Smith PL, Torbenson MS, Polotsky VY. Chronic intermittent hypoxia causes hepatitis in a mouse model of diet-induced fatty liver. Am J Physiol Gastrointest Liver Physiol. 2007; 293:G871-G877.

Obstructive sleep apnea (OSA) causes chronic intermittent hypoxia (CIH) during sleep. OSA is associated with nonalcoholic steatohepatitis (NASH) in obese individuals and may contribute to progression of nonalcoholic fatty liver disease from steatosis to NASH. The purpose of this study was to examine...

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Bibliographic Details
Main Authors: Daniel Zamora-Valdés, Nahum Méndez-Sánchez
Format: Article
Language:English
Published: Elsevier 2007-10-01
Series:Annals of Hepatology
Subjects:
Obstructive sleep apnea
nonalcoholic steato-hepatitis
obesity
liver
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119319143

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http://www.sciencedirect.com/science/article/pii/S1665268119319143

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