Polysaccharide-containing fraction from Artemisia argyi inhibits tumor cell-induced platelet aggregation by blocking interaction of podoplanin with C-type lectin-like receptor 2

Tumor cell-induced platelet aggregation (TCIPA) is a mechanism that involves the protection of tumor cells in the circulation and the promotion of tumor cell invasion and metastases. The C-type lectin-like receptor 2 (CLEC-2) that binds podoplanin (PDPN) is on the platelet surface and facilitates th...

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Bibliographic Details
Main Authors: Ching-Ping Tseng, Yu-Ling Huang, Yao-Wen Chang, Hsiang-Ruei Liao, Yu-Li Chen, Pei-Wen Hsieh
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of Food and Drug Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S102194981930081X