Parsing the IL-37-Mediated Suppression of Inflammasome Function

Parsing the IL-37-Mediated Suppression of Inflammasome Function

Interleukin (IL)-37 is a member of the IL-1 family of cytokines. Although its broad anti-inflammatory properties are well described, the effects of IL-37 on inflammasome function remain poorly understood. Performing gene expression analyses, ASC oligomerization/speck assays and caspase-1 assays in b...

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Bibliographic Details
Main Authors: Ina Rudloff, Holly K. Ung, Jennifer K. Dowling, Ashley Mansell, Laura D’Andrea, Andrew M. Ellisdon, James C. Whisstock, Philip J. Berger, Claudia A. Nold-Petry, Marcel F. Nold
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
interleukin 37
interleukin 1β
interleukin 18
inflammasome
asc
caspase-1
pyroptosis
nlrp3
aim2
Online Access:https://www.mdpi.com/2073-4409/9/1/178

Internet

https://www.mdpi.com/2073-4409/9/1/178

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