Study of Validity of PC-3 Derived Xenograft Tumor Model in Athymic Nude Mice for Targeting Therapy of Androgen Receptors in Preclinical Studies of Prostate Cancer
Background: Androgen receptors (AR) play an important role in proliferation of cancerous prostatic cells and prevention of apoptotic signaling. Current drugs cannot inhibit the activity of these receptors very well. Establishment of appropriate animal models is essential for discovery of new drugs...
Main Authors: | Samad Muhammadnejad, Ahad Muhammadnejad, Zohreh Mazaheri, Farrokh Tirgari, Mohammad-Ali Oghabian, Maryam Kazem haghighi, Saeid Amanpour |
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Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2016-10-01
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Series: | Basic & Clinical Cancer Research |
Subjects: | |
Online Access: | https://bccr.tums.ac.ir/index.php/bccrj/article/view/19 |
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