A proteomic approach to understanding the pathogenesis of idiopathic macular hole formation

Abstract Idiopathic macular holes (IMH) are full-thickness defects of retinal tissue that cause severe vision loss due to disruption of the anatomic fovea. Abnormal vitreous traction is involved in the formation of macular holes. Both glial cells and hyalocytes contribute to epiretinal membrane form...

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Bibliographic Details
Main Authors: Pingbo Zhang, Min Zhu, Yuming Zhao, Jiang Qian, Craig Dufresne, Randi Turner, Richard D. Semba, Sharon D. Solomon
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Clinical Proteomics
Subjects:
Eye
Online Access:http://link.springer.com/article/10.1186/s12014-017-9172-y