Role of macrophages in the altered epithelial function during a type 2 immune response induced by enteric nematode infection.

Role of macrophages in the altered epithelial function during a type 2 immune response induced by enteric nematode infection.

Parasitic enteric nematodes induce a type 2 immune response characterized by increased production of Th2 cytokines, IL-4 and IL-13, and recruitment of alternatively activated macrophages (M2) to the site of infection. Nematode infection is associated with changes in epithelial permeability and inhib...

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Bibliographic Details
Main Authors: Luigi Notari, Diana C Riera, Rex Sun, Jennifer A Bohl, Leon P McLean, Kathleen B Madden, Nico van Rooijen, Tim Vanuytsel, Joseph F Urban, Aiping Zhao, Terez Shea-Donohue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3900397?pdf=render

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http://europepmc.org/articles/PMC3900397?pdf=render

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