MCP/CCR2 signaling is essential for recruitment of mesenchymal progenitor cells during the early phase of fracture healing.

OBJECTIVE: The purpose of this study was to investigate chemokine profiles and their functional roles in the early phase of fracture healing in mouse models. METHODS: The expression profiles of chemokines were examined during fracture healing in wild-type (WT) mice using a polymerase chain reaction...

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Main Authors: Masahiro Ishikawa, Hiromu Ito, Toshiyuki Kitaori, Koichi Murata, Hideyuki Shibuya, Moritoshi Furu, Hiroyuki Yoshitomi, Takayuki Fujii, Koji Yamamoto, Shuichi Matsuda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4136826?pdf=render