Stability and Hopf bifurcations in a competitive tumour-immune system with intrinsic recruitment delay and chemotherapy

Stability and Hopf bifurcations in a competitive tumour-immune system with intrinsic recruitment delay and chemotherapy

In this paper, a three-dimensional nonlinear delay differential system including Tumour cells, cytotoxic-T lymphocytes, T-helper cells is constructed to investigate the effects of intrinsic recruitment delay and chemotherapy. It is found that the introduction of chemotherapy and time delay can gener...

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Bibliographic Details
Main Authors: Qingfeng Tang, Guohong Zhang
Format: Article
Language:English
Published: AIMS Press 2021-04-01
Series:Mathematical Biosciences and Engineering
Subjects:
bistable phenomenon
tumor relapse
intrinsic recruitment delay
chemotherapy
hopf bifurcation
numerical simulations
Online Access:http://www.aimspress.com/article/doi/10.3934/mbe.2021101?viewType=HTML

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http://www.aimspress.com/article/doi/10.3934/mbe.2021101?viewType=HTML

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