Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamous cell carcinoma

Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamous cell carcinoma

Background Checkpoint inhibitors targeting programmed death receptor-1 (PD-1) have been tested in the neoadjuvant setting for the treatment of locoregionally advanced head and neck squamous cell carcinoma (HNSCC); however, response rates are modest. We hypothesized that adding stereotactic body radi...

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Bibliographic Details
Main Authors: Allen C Cheng, Hong Xiao, Marka Crittenden, Carlo Bifulco, Michael Gough, Kristina Young, Walter J Urba, R Bryan Bell, Yaping Wu, George Morris, Marcus A Couey, Ashish A Patel, Amber L Watters, Lessli Rushforth, Shorin Nemeth
Format: Article
Language:English
Published: BMJ Publishing Group 2021-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/5/e002485.full

Internet

https://jitc.bmj.com/content/9/5/e002485.full

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