Deregulation of Hepatic Mek1/2–Erk1/2 Signaling Module in Iron Overload Conditions

The liver, through the production of iron hormone hepcidin, controls body iron levels. High liver iron levels and deregulated hepcidin expression are commonly observed in many liver diseases including highly prevalent genetic iron overload disorders. In spite of a number of breakthrough investigatio...

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Bibliographic Details
Main Authors: Naveen Kumar Tangudu, Nils Buth, Pavel Strnad, Ion C. Cirstea, Maja Vujić Spasić
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Pharmaceuticals
Subjects:
Hfe
Online Access:https://www.mdpi.com/1424-8247/12/2/70