Antidiabetic Effect of Casein Glycomacropeptide Hydrolysates on High-Fat Diet and STZ-Induced Diabetic Mice via Regulating Insulin Signaling in Skeletal Muscle and Modulating Gut Microbiota

Antidiabetic Effect of Casein Glycomacropeptide Hydrolysates on High-Fat Diet and STZ-Induced Diabetic Mice via Regulating Insulin Signaling in Skeletal Muscle and Modulating Gut Microbiota

This study evaluated the effects and the underlying mechanisms of casein glycomacropeptide hydrolysate (GHP) on high-fat diet-fed and streptozotocin-induced type 2 diabetes (T2D) in C57BL/6J mice. Results showed that 8-week GHP supplementation significantly decreased fasting blood glucose levels, re...

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Bibliographic Details
Main Authors: Qichen Yuan, Biyuan Zhan, Rui Chang, Min Du, Xueying Mao
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Nutrients
Subjects:
casein glycomacropeptide hydrolysate
diabetes
insulin signaling pathway
skeletal muscle
gut microbiota
inflammation
Online Access:https://www.mdpi.com/2072-6643/12/1/220

Internet

https://www.mdpi.com/2072-6643/12/1/220

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