Mortality in COVID-19 disease patients: Correlating the association of major histocompatibility complex (MHC) with severe acute respiratory syndrome 2 (SARS-CoV-2) variants

Mortality in COVID-19 disease patients: Correlating the association of major histocompatibility complex (MHC) with severe acute respiratory syndrome 2 (SARS-CoV-2) variants

Genetic factors such as the HLA type of patients may play a role in regard to disease severity and clinical outcome of patients with COVID-19. Taking the data deposited in the GISAID database, we made predictions using the IEDB analysis resource (TepiTool) to gauge how variants in the SARS-CoV-2 gen...

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Bibliographic Details
Main Authors: Eric de Sousa, Dário Ligeiro, Joana R. Lérias, Chao Zhang, Chiara Agrati, Mohamed Osman, Sherif A. El-Kafrawy, Esam I. Azhar, Giuseppe Ippolito, Fu-Sheng Wang, Alimuddin Zumla, Markus Maeurer
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:International Journal of Infectious Diseases
Subjects:
SARS-CoV-2
COVID-19
SARS
T-cells
MHC
HLA
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971220305609

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http://www.sciencedirect.com/science/article/pii/S1201971220305609

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