Activation of PKC-e counteracts maturation and apoptosis of HL-60 myeloid leukemic cells in response to TNF family members

Protein kinase C (PKC)-e, a component of the serine/threonine PKC family, has been shown to influence the survival and differentiation pathways of normal hematopoietic cells. Here, we have modulated the activity of PKC-e with specific small molecule activator or inhibitor peptides. PKC-e inhibitor a...

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Bibliographic Details
Main Authors: A. Gonelli, D. Milani, E. Rimondi, R. Voltan, V. Grill, C. Celeghini
Format: Article
Language:English
Published: PAGEPress Publications 2009-09-01
Series:European Journal of Histochemistry
Online Access:http://www.ejh.it/index.php/ejh/article/view/1336