Polymorphism in the Promoter Region of the IL18 Gene and the Association With Severity on Paracoccidioidomycosis

Polymorphism in the Promoter Region of the IL18 Gene and the Association With Severity on Paracoccidioidomycosis

Paracoccidioidomycosis (PCM) is an important endemic, systemic disease in Latin America caused by Paracoccidioides spp. This mycosis has been associated with high morbidity and sequels, and its clinical manifestations depend on the virulence of the infecting strain, the degree and type of immune res...

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Bibliographic Details
Main Authors: Paula Keiko Sato, Felipe Delatorre Busser, Flávia Mendes da Cunha Carvalho, Alexandra Gomes dos Santos, Aya Sadahiro, Constancia Lima Diogo, Adriana Satie Gonçalves Kono, Maria Luiza Moretti, Olinda do Carmo Luiz, Maria Aparecida Shikanai-Yasuda
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
paracoccidioidomycosis
Paracoccidioides spp.
single nucleotide polymophism
IL18
IL12A
IFNGR1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.542210/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.542210/full

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