Differential site accessibility mechanistically explains subcellular-specific N-glycosylation determinants

Glycoproteins perform extra- and intracellular functions in innate and adaptive immunity by lectin-based interactions to exposed glyco-determinants. Herein, we document and mechanistically explain the formation of subcellular-specific N-glycosylation determinants on glycoproteins trafficking through...

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Bibliographic Details
Main Authors: Ling Yen Lee, Chi-Hung eLin, Susan eFanayan, Nicolle H. Packer, Morten eThaysen-Andersen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00404/full