HIV Antibody Fc N-Linked Glycosylation Is Associated with Viral Rebound

HIV Antibody Fc N-Linked Glycosylation Is Associated with Viral Rebound

Summary: Changes in antibody glycosylation are linked to inflammation across several diseases. Alterations in bulk antibody galactosylation can predict rheumatic flares, act as a sensor for immune activation, predict gastric cancer relapse, track with biological age, shift with vaccination, change w...

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Bibliographic Details
Main Authors: Rasmus Offersen, Wen-Han Yu, Eileen P. Scully, Boris Julg, Zelda Euler, Saheli Sadanand, Dario Garcia-Dominguez, Lu Zheng, Thomas A. Rasmussen, Madeleine F. Jennewein, Caitlyn Linde, Jessica Sassic, Giuseppe Lofano, Selena Vigano, Kathryn E. Stephenson, Stephanie Fischinger, Todd J. Suscovich, Mathias Lichterfeld, Douglas Lauffenburger, Erik S. Rosenberg, Todd Allen, Marcus Altfeld, Richelle C. Charles, Lars Østergaard, Martin Tolstrup, Dan H. Barouch, Ole S. Søgaard, Galit Alter
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Cell Reports
Subjects:
HIV
antibodies
glycosylation
viral host response
biomarkers
cure
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720314911

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http://www.sciencedirect.com/science/article/pii/S2211124720314911

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