Prognostic value of programmed death-1, programmed death-ligand 1, programmed death-ligand 2 expression, and CD8(+) T cell density in primary tumors and metastatic lymph nodes from patients with stage T1-4N+M0 gastric adenocarcinoma

Prognostic value of programmed death-1, programmed death-ligand 1, programmed death-ligand 2 expression, and CD8(+) T cell density in primary tumors and metastatic lymph nodes from patients with stage T1-4N+M0 gastric adenocarcinoma

Abstract Background Anti-programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) immunotherapy has been proved to be effective on gastric cancer in ongoing clinical trials. However, the value of PD-L1 in predicting responses of patients with gastric cancer to anti-PD-1/PD-L1 immunotherapy is contr...

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Bibliographic Details
Main Authors: Yuan Gao, Su Li, Dazhi Xu, Shangxiang Chen, Yuchen Cai, Wenqi Jiang, Xinke Zhang, Jin Sun, Kefeng Wang, Boyang Chang, Fenghua Wang, Minghuang Hong
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Chinese Journal of Cancer
Subjects:
Gastric cancer
Programmed cell death-ligand 1
Programmed cell death-ligand 2
Programmed cell death-1
CD8(+) T cells
Heterogeneity expression
Online Access:http://link.springer.com/article/10.1186/s40880-017-0226-3

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http://link.springer.com/article/10.1186/s40880-017-0226-3

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