Requirement of TORC1 for late-phase long-term potentiation in the hippocampus.

Requirement of TORC1 for late-phase long-term potentiation in the hippocampus.

Late-phase long-term potentiation (L-LTP) and long-term memory depend on the transcription of mRNA of CRE-driven genes and synthesis of proteins. However, how synaptic signals propagate to the nucleus is unclear. Here we report that the CREB coactivator TORC1 (transducer of regulated CREB activity 1...

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Bibliographic Details
Main Authors: Yang Zhou, Hao Wu, Shuai Li, Qian Chen, Xue-Wen Cheng, Jing Zheng, Hiroshi Takemori, Zhi-Qi Xiong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1762377?pdf=render

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http://europepmc.org/articles/PMC1762377?pdf=render

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