An epigenomic landscape of cervical intraepithelial neoplasia and cervical cancer using single‐base resolution methylome and hydroxymethylome

An epigenomic landscape of cervical intraepithelial neoplasia and cervical cancer using single‐base resolution methylome and hydroxymethylome

Abstract Background Cervical cancer (CC) is the second leading cause of cancer death among women worldwide. Epigenetic regulation of gene expression through DNA methylation and hydroxymethylation plays a pivotal role during tumorigenesis. In this study, to analyze the epigenomic landscape and identi...

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Bibliographic Details
Main Authors: Yingxin Han, Liyan Ji, Yanfang Guan, Mengya Ma, Pansong Li, Yinge Xue, Yinxin Zhang, Wanqiu Huang, Yuhua Gong, Li Jiang, Xipeng Wang, Hong Xie, Boping Zhou, Jiayin Wang, Junwen Wang, Jinghua Han, Yuliang Deng, Xin Yi, Fei Gao, Jian Huang
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Clinical and Translational Medicine
Subjects:
cervical cancer
cervical intraepithelial neoplasia
DhMR
DMR
hydroxymethylation
methylation
Online Access:https://doi.org/10.1002/ctm2.498

Internet

https://doi.org/10.1002/ctm2.498

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