Sequential conformational transitions and α-helical supercoiling regulate a sensor histidine kinase

Sequential conformational transitions and α-helical supercoiling regulate a sensor histidine kinase

Sensor histidine kinases (SHK) consist of sensor, linker and kinase modules and different models for SHK signal transduction have been proposed. Here the authors present nano- to millisecond time-resolved X-ray scattering measurements, which reveal a structural mechanism for kinase domain activation...

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Bibliographic Details
Main Authors: Oskar Berntsson, Ralph P. Diensthuber, Matthijs R. Panman, Alexander Björling, Emil Gustavsson, Maria Hoernke, Ashley J. Hughes, Léocadie Henry, Stephan Niebling, Heikki Takala, Janne A. Ihalainen, Gemma Newby, Silke Kerruth, Joachim Heberle, Marianne Liebi, Andreas Menzel, Robert Henning, Irina Kosheleva, Andreas Möglich, Sebastian Westenhoff
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00300-5

Internet

https://doi.org/10.1038/s41467-017-00300-5

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