Intracolic ultrasound molecular imaging: a novel method for assessing colonic tumor necrosis factor-α expression in inflammatory bowel disease

Abstract Background While anti-tumor necrosis factor alpha (TNF-α) therapy has been proven effective in inflammatory bowel disease (IBD), approximately 40% of patients lose the response. Transmembrane TNF-α (mTNF-α) expression in the intestinal mucosa is correlated with therapeutic efficacy, and qua...

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Bibliographic Details
Main Authors: Xiaoyan Miao, Ren Mao, Yujia You, Huichao Zhou, Chen Qiu, Xuehua Li, Zhihui Chen, Jie Ren, Minhu Chen, Ping Wang, Rongqin Zheng, Tinghui Yin
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-021-00379-z