Down-regulation of EBV-LMP1 radio-sensitizes nasal pharyngeal carcinoma cells via NF-κB regulated ATM expression.

BACKGROUND:The latent membrane protein 1 (LMP1) encoded by EBV is expressed in the majority of EBV-associated human malignancies and has been suggested to be one of the major oncogenic factors in EBV-mediated carcinogenesis. In previous studies we experimentally demonstrated that down-regulation of...

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Bibliographic Details
Main Authors: Xiaoqian Ma, Lifang Yang, Lanbo Xiao, Min Tang, Liyu Liu, Zijian Li, Mengyao Deng, Lunquan Sun, Ya Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3212510?pdf=render