Quantitative detection and biological propagation of scrapie seeding activity in vitro facilitate use of prions as model pathogens for disinfection.

Prions are pathogens with an unusually high tolerance to inactivation and constitute a complex challenge to the re-processing of surgical instruments. On the other hand, however, they provide an informative paradigm which has been exploited successfully for the development of novel broad-range disin...

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Bibliographic Details
Main Authors: Sandra Pritzkow, Katja Wagenführ, Martin L Daus, Susann Boerner, Karin Lemmer, Achim Thomzig, Martin Mielke, Michael Beekes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3103549?pdf=render