Social learning promotes nicotine self-administration by facilitating the extinction of conditioned aversion in isogenic strains of rats

Abstract Both social environment and genetic factors are critical for smoking initiation and nicotine addiction. We reported that rats developed conditioned flavor (i.e., taste and odor) aversion to intravenously self-administered (IVSA) nicotine, and that social learning promoted nicotine IVSA with...

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Bibliographic Details
Main Authors: Wenyan Han, Tengfei Wang, Hao Chen
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08291-5