Pharmacokinetic and urinary profiling reveals the prednisolone/cortisol ratio as a valid biomarker for prednisolone administration

Pharmacokinetic and urinary profiling reveals the prednisolone/cortisol ratio as a valid biomarker for prednisolone administration

Abstract Background In Europe, synthetic corticosteroids are not allowed in animal breeding for growth-promoting purposes. Nevertheless, a high prevalence of non-compliant urine samples was recently reported for prednisolone, however, without any indication of unauthorized use. Within this context,...

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Bibliographic Details
Main Authors: Lieven Van Meulebroek, Nathalie De Clercq, Julie Vanden Bussche, Mathias Devreese, Eric Fichant, Philippe Delahaut, Siska Croubels, Lynn Vanhaecke
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Veterinary Research
Subjects:
Glucocorticoids
Prednisolone
Screening tools
Prednisolone/cortisol ratio
20β-dihydroprednisolone
Adrenocorticotropic hormone
Online Access:http://link.springer.com/article/10.1186/s12917-017-1158-5

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http://link.springer.com/article/10.1186/s12917-017-1158-5

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