Phylogenetic Study of Polyketide Synthases and Nonribosomal Peptide Synthetases Involved in the Biosynthesis of Mycotoxins

Phylogenetic Study of Polyketide Synthases and Nonribosomal Peptide Synthetases Involved in the Biosynthesis of Mycotoxins

Polyketide synthase (PKSs) and nonribosomal peptide synthetase (NRPSs) are large multimodular enzymes involved in biosynthesis of polyketide and peptide toxins produced by fungi. Furthermore, hybrid enzymes, in which a reducing PKS region is fused to a single NRPS module, are also responsible of the...

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Bibliographic Details
Main Authors: Massimo Ferrara, Antonia Gallo, Giancarlo Perrone
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Toxins
Subjects:
polyketide synthase
non-ribosomal peptide synthetase
phylogenies
β-ketosynthase
acyl-transferase
adenylation
condensation
secondary metabolites
Online Access:http://www.mdpi.com/2072-6651/5/4/717

Internet

http://www.mdpi.com/2072-6651/5/4/717

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