Quantitative Description of Surface Complementarity of Antibody-Antigen Interfaces

Antibodies have the remarkable ability to recognise their cognate antigens with extraordinary affinity and specificity. Discerning the rules that define antibody-antigen recognition is a fundamental step in the rational design and engineering of functional antibodies with desired properties. In this...

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Bibliographic Details
Main Authors: Lorenzo Di Rienzo, Edoardo Milanetti, Giancarlo Ruocco, Rosalba Lepore
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.749784/full