HPV16-E2 protein modifies self-renewal and differentiation rate in progenitor cells of human immortalized keratinocytes

Abstract Background Cervical cancer is the fourth cause of death worldwide by cancer in women and is a disease associated to persistent infection with human papillomavirus (HPV), particularly from two high-risk types HPV16 and 18. The virus initiates its replicative cycle infecting cells located in...

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Bibliographic Details
Main Authors: Victoria Domínguez-Catzín, Alicia-María Reveles-Espinoza, Janet Sánchez-Ramos, Raúl Cruz-Cadena, Diana Lemus-Hernández, Efraín Garrido
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Virology Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12985-017-0736-2