Cisplatin-loaded mPEG-PCL Nanoparticles: Relation of PEG-PCL/PCL Hybrid Proportions and Antitumor Activity in Vitro

Cisplatin-loaded mPEG-PCL Nanoparticles: Relation of PEG-PCL/PCL Hybrid Proportions and Antitumor Activity in Vitro

Objective To prepare cisplatin-loaded mPEG-PCL nanoparticles with different proportions of bi-block copolymer mPEG-PCL and PCL, and evaluate their antitumor effect in vitro. Methods mPEG-PCL and HO-PCL were synthesized by ring-opening polymerization method. Nanoparticles (NPs) prepared from mPEG-PCL...

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Bibliographic Details
Main Authors: WANG Chun, YU Lixia, WANG Lifeng, QIAN Hanqing, YAN Yingci, WANG Xinyue, LI Rutian
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2020-06-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
cisplatin
nanoparticles
w/o/w double-emulsion method
drug-delivery system
antitumor
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2020.19.0979.htm

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http://html.rhhz.net/ZLFZYJ/html/8578.2020.19.0979.htm

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